Take a look at how all the match-day squads shape up ahead of the second-round fixtures in the Six Nations this weekend.
England – 15 Elliot Daly, 14 Anthony Watson, 13 Henry Slade, 12 Owen Farrell (c), 11 Jonny May, 10 George Ford, 9 Ben Youngs, 8 Billy Vunipola, 7 Tom Curry, 6 Courtney Lawes, 5 Jonny Hill, 4 Maro Itoje, 3 Kyle Sinkler, 2 Luke Cowan-Dickie, 1 Mako Vunipola.
Subs: 16 Jamie George, 17 Ellis Genge, 18 Will Stuart, 19 Courtney Lawes, 20 Ben Earl, 21 Dan Robson, 22 George Ford, 23 Max Malins.
READ: England revert to Ford-Farrell partnership against Italy
Italy – 15 Jacapo Trulla, 14 Luca Sperandio, 13 Ignacio Brex, 12 Carlo Canna, 11 Monty Ioane, 10 Paolo Garbisi, 9 Stephen Varney, 8 Michele Lamaro, 7 Johan Meyer, 6 Sebastian Negri, 5 David Sisi, 4 Marco Lazzaroni, 3 Marco Riccioni, 2 Luca Bigi (c), 1 Andrea Lovotti
Subs: 16 Gianmarco Luccesi, 17 Danilo Fischetti, 18 Giosue Zilocchi, 19 Niccolo Cannone, 20 Frederico Ruzza, 21 Guglielmo Palazzani, 22 Tommaso Allan, 23 Frederico Mori
Wales – 15 Leigh Halfpenny, 14 Louis Rees-Zammit, 13 Owen Watkin, 12 Nick Tompkins, 11 Liam Williams, 10 Dan Biggar, 9 Gareth Davies, 8 Taulupe Faletau, 7 Justin Tipuric, 6 Aaron Wainwright, 5 Alun Wyn Jones (c), 4 Adam Beard, 3 Tomas Francis, 2 Ken Owens, 1 Wyn Jones.
Subs: 16 Elliot Dee, 17 Rhodri Jones, 18 Leon Brown, 19 Will Rowlands, 20 James Botham, 21 Kieran Hardy, 22 Callum Sheedy, 23 Willis Halaholo.
READ: Changes for injury-hit Wales
Scotland – 15 Stuart Hogg (c), 14 Darcy Graham, 13 Chris Harris, 12 James Lang, 11 Duhan van der Merwe, 10 Finn Russell, 9 Ali Price, 8 Matt Fagerson, 7 Hamish Watson, 6 Blade Thomson, 5 Jonny Gray, 4 Scott Cummings, 3 Zander Fagerson, 2 George Turner, 1 Rory Sutherland.
Subs: 16 David Cherry, 17 Oli Kebble, 18 WP Nel, 19 Richie Gray, 20 Gary Graham, 21 Scott Steele, 22 Jaco van der Walt, 23 Huw Jones.
READ: Injuries force Scotland into multiple changes
Ireland – TBC
France – TBC