Pat McCabe and Clyde Rathbone will start for the Brumbies against the Rebels in Canberra on Saturday.
McCabe comes in at fullback with Jesse Mogg dropping down to the bench, while Rathbone appears on the left wing in place of Robbie Coleman for his first appearance of the season.
The other change sees Ruan Smith win a spot at tighthead prop ahead of Wallaby Ben Alexander, after impressing off the bench.
Meanwhile, the Rebels welcome back experienced duo Tamati Ellison and Laurie Weeks. Weeks returns after a one-week absence from an ankle injury, while Ellison has recovered from a minor knee knock suffered in training last week.
Brumbies – 15 Pat McCabe, 14 Henry Speight, 13 Tevita Kuridrani, 12 Christian Leali'ifano, 11 Clyde Rathbone, 10 Matt Toomua, 9 Nic White, 8 Ben Mowen (c), 7 Jarrad Butler, 6 Fotu Auelua, 5 Scott Fardy, 4 Sam Carter, 3 Ruan Smith, 2 Stephen Moore, 1 Scott Sio.
Subs: 16 Josh Mann-Rea, 17 JP Smith, 18 Ben Alexander, 19 Leon Power, 20 Jordan Smiler, 21 Michael Dowsett, 22 Andrew Smith, 23 Jesse Mogg.
Rebels – 15 Jason Woodward, 14 Male Sau, 13 Tamati Ellison, 12 Mitch Inman, 11 Tom English, 10 Bryce Hegarty, 9 Ben Meehan, 8 Scott Higginbotham (c), 7 Scott Fuglistaller, 6 Colby Fainga'a, 5 Luke Jones, 4 Caderyn Neville, 3 Laurie Weeks, 2 Pat Leafa, 1 Toby Smith.
Subs: 16 Shota Horie, 17 Cruze Ah-Nau, 18 Paul Alo-Emile, 19 Hugh Pyle, 20 Jordy Reid, 21 Josh Holmes, 22 Jack Debreczeni, 23 Tom Kingston.
Photo: Scott Barbour/Getty Images