Mike Brown will start at fullback in one of two changes to the England side to face Scotland at Twickenham on Saturday.
Brown, who suffered a head injury in England's 47-17 win over Italy and missed the subsequent match against Ireland in Dublin two weeks later, is fit again and comes into the team for Alex Goode.
Elsewhere, second row Courtney Lawes will make his first appearance in this year's Six Nations in place of George Kruis.
Coach Stuart Lancaster has also made three changes to the bench, with Tom Wood taking the place of the injured Tom Croft, while Geoff Parling and Kieran Brookes come in ahead of Nick Easter and Henry Thomas, respectively.
England – 15 Mike Brown, 14 Anthony Watson, 13 Jonathan Joseph, 12 Luther Burrell, 11 Jack Nowell, 10 George Ford, 9 Ben Youngs, 8 Billy Vunipola, 7 Chris Robshaw (c), 6 James Haskell, 5 Courtney Lawes, 4 Dave Attwood, 3 Dan Cole, 2 Dylan Hartley, 1 Joe Marler.
Subs: 16 Tom Youngs, 17 Mako Vunipola, 18 Kieran Brookes, 19 Geoff Parling, 20 Tom Wood, 21 Richard Wigglesworth, 22 Danny Cipriani, 23 Billy Twelvetrees.
Photo: David Rogers/Getty Images